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532 However, the overexpression of SIRT1 displays protection against abnormal motor function, cortical and striatal atrophy and loss of striatal neurons in the transgenic HD mice via regulating mitochondrial function
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It was originally derived from a protein fragment associated with gastric juice and studied for its protective effects on the gastrointestinal system.¹ Since its development in the 1990s, research has expanded into musculoskeletal healing, where it has shown promising effects in animal models involving tendon, ligament, muscle, and bone injuries.² One important caveat regarding BPC-157 is that it is not FDA-approved for human use, and most of what we know comes from preclinical research
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