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The authors revealed that mature RBCs express key components of the extrinsic apoptosis pathway, including Fas, FasL, FADD, and caspase-8 and caspase-3 (Fig
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In Vivo Study Taking into consideration the results from the series of screening studies above, Compound 1.70 was selected for in vivo study as it showed retention in activity with all of the key enzymes (GST, GPx, and GR) while also displaying improved stability, as opposed to the other compounds that had lost activity with one or more key enzymes
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