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In studies at the University of California at San Francisco, young (age 20–25), male medical students were found to have about 200 nanograms/mL of GHK in their blood plasma, while the healthy, male medical school faculty (average age of 60) had only 80 nanograms/mL [7]

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NNMT inhibition follows dose-dependent curves: 50mg produces 40–50% enzyme inhibition, 100mg achieves 60–75%, with diminishing returns beyond 150mg